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An atypical residue in the pore of Varroa destructor GABA-activated RDL receptors affects picrotoxin block and thymol modulation

GABA-activated RDL receptors are the insect equivalent of mammalian GABA(A) receptors, and play a vital role in neurotransmission and insecticide action. Here we clone the pore lining M2 region of the Varroa mite RDL receptor and show that it has 4 atypical residues when compared to M2 regions of mo...

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Detalles Bibliográficos
Autores principales: Price, Kerry L., Lummis, Sarah C.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261083/
https://www.ncbi.nlm.nih.gov/pubmed/25460510
http://dx.doi.org/10.1016/j.ibmb.2014.10.002