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The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1,25-dihydroxyvitamin D-directed transcriptional events in osteoblasts

Heterogeneous nuclear ribonucleoprotein (hnRNP) C plays a key role in RNA processing but also exerts a dominant negative effect on responses to 1,25-dihydroxyvitamin D (1,25(OH)(2)D) by functioning as a vitamin D response element-binding protein (VDRE-BP). hnRNPC acts a tetramer of hnRNPC1 (huC1) an...

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Detalles Bibliográficos
Autores principales: Lisse, Thomas S, Vadivel, Kanagasabai, Bajaj, S Paul, Zhou, Rui, Chun, Rene F, Hewison, Martin, Adams, John S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261231/
https://www.ncbi.nlm.nih.gov/pubmed/25506471
http://dx.doi.org/10.1038/boneres.2014.11