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Secondary structure of the Irf7 5’-UTR, analyzed using SHAPE (selective 2’-hydroxyl acylation analyzed by primer extension)

OASL1 is a member of the 2’-5’-oligoadenylate synthetase (OAS) family and promotes viral clearance by activating RNase L. OASL1 interacts with the 5’-untranslated region (UTR) of interferon regulatory factor 7 (Irf7) and inhibits its translation. To identify the secondary structure required for OASL...

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Detalles Bibliográficos
Autores principales: Kim, Yun-Mi, Choi, Won-Young, Oh, Chang-Mok, Han, Gyoon-Hee, Kim, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261513/
https://www.ncbi.nlm.nih.gov/pubmed/24393529
http://dx.doi.org/10.5483/BMBRep.2014.47.10.281