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PEP-1-HO-1 prevents MPTP-induced degeneration of dopaminergic neurons in a Parkinson’s disease mouse model

Heme oxygenase-1 (HO-1) degrades heme to carbon dioxide, biliverdin, and Fe(2+), which play important roles in various biochemical processes. In this study, we examined the protective function of HO-1 against oxidative stress in SH-SY5Y cells and in a Parkinson’s disease mouse model. Western blot an...

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Detalles Bibliográficos
Autores principales: Youn, Jong Kyu, Kim, Dae Won, Kim, Seung Tae, Park, Sung Yeon, Yeo, Eun Ji, Choi, Yeon Joo, Lee, Hae-Ran, Kim, Duk-Soo, Cho, Sung-Woo, Han, Kyu Hyung, Park, Jinseu, Eum, Won Sik, Hwang, Hyun Sook, Choi, Soo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261515/
https://www.ncbi.nlm.nih.gov/pubmed/24499676
http://dx.doi.org/10.5483/BMBRep.2014.47.10.286