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Olanzapine-induced methylation alters cadherin gene families and associated pathways implicated in psychosis

BACKGROUND: The complex aetiology of most mental disorders involves gene-environment interactions that may operate using epigenetic mechanisms particularly DNA methylation. It may explain many of the features seen in mental disorders including transmission, expression and antipsychotic treatment res...

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Detalles Bibliográficos
Autores principales: Melka, Melkaye G, Castellani, Christina A, Rajakumar, Nagalingam, O’Reilly, Richard, Singh, Shiva M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261529/
https://www.ncbi.nlm.nih.gov/pubmed/25266742
http://dx.doi.org/10.1186/1471-2202-15-112