Gastroretentive Pulsatile Release Tablets of Lercanidipine HCl: Development, Statistical Optimization, and In Vitro and In Vivo Evaluation

The present study was aimed at the development of gastroretentive floating pulsatile release tablets (FPRTs) of lercanidipine HCl to enhance the bioavailability and treat early morning surge in blood pressure. Immediate release core tablets containing lercanidipine HCl were prepared and optimized co...

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Detalles Bibliográficos
Autores principales: Reddy, Gagganapalli Santhoshi, Nayak, Usha Yogendra, Deshpande, Praful Balavant, Mutalik, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261557/
https://www.ncbi.nlm.nih.gov/pubmed/25525619
http://dx.doi.org/10.1155/2014/421931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261557/
https://www.ncbi.nlm.nih.gov/pubmed/25525619
http://dx.doi.org/10.1155/2014/421931

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