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Gastroretentive Pulsatile Release Tablets of Lercanidipine HCl: Development, Statistical Optimization, and In Vitro and In Vivo Evaluation
The present study was aimed at the development of gastroretentive floating pulsatile release tablets (FPRTs) of lercanidipine HCl to enhance the bioavailability and treat early morning surge in blood pressure. Immediate release core tablets containing lercanidipine HCl were prepared and optimized co...
Autores principales: | Reddy, Gagganapalli Santhoshi, Nayak, Usha Yogendra, Deshpande, Praful Balavant, Mutalik, Srinivas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261557/ https://www.ncbi.nlm.nih.gov/pubmed/25525619 http://dx.doi.org/10.1155/2014/421931 |
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