c-FLIP is involved in tumor progression of peripheral T-cell lymphoma and targeted by histone deacetylase inhibitors

BACKGROUND: Peripheral T-cell lymphomas (PTCLs) are often aggressive tumors and resistant to conventional chemotherapy. Dysregulation of extrinsic apoptosis plays an important role on tumor cell sensitivity to chemotherapeutic agents. Cellular FLICE inhibitory protein (c-FLIP) is a key regulator of...

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Detalles Bibliográficos
Autores principales: Zheng, Zhong, Cheng, Shu, Wu, Wen, Wang, Li, Zhao, Yan, Shen, Yang, Janin, Anne, Zhao, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261569/
https://www.ncbi.nlm.nih.gov/pubmed/25477070
http://dx.doi.org/10.1186/s13045-014-0088-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261569/
https://www.ncbi.nlm.nih.gov/pubmed/25477070
http://dx.doi.org/10.1186/s13045-014-0088-y

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