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c-FLIP is involved in tumor progression of peripheral T-cell lymphoma and targeted by histone deacetylase inhibitors
BACKGROUND: Peripheral T-cell lymphomas (PTCLs) are often aggressive tumors and resistant to conventional chemotherapy. Dysregulation of extrinsic apoptosis plays an important role on tumor cell sensitivity to chemotherapeutic agents. Cellular FLICE inhibitory protein (c-FLIP) is a key regulator of...
Autores principales: | Zheng, Zhong, Cheng, Shu, Wu, Wen, Wang, Li, Zhao, Yan, Shen, Yang, Janin, Anne, Zhao, Wei-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261569/ https://www.ncbi.nlm.nih.gov/pubmed/25477070 http://dx.doi.org/10.1186/s13045-014-0088-y |
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