The dUTPase-related gene of bovine immunodeficiency virus is critical for viral replication, despite the lack of dUTPase activity of the encoded protein

BACKGROUND: Deoxyuridine 5′-triphosphate nucleotide-hydrolases (dUTPases) are essential for maintaining low intra-cellular dUTP/dTTP ratios. Therefore, many viruses encode this enzyme to prevent dUTP incorporation into their genomes instead of dTTP. Among the lentiviruses, the non-primate viruses ex...

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Detalles Bibliográficos
Autores principales: Voronin, Nickolay, Herzig, Eytan, Hizi, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261571/
https://www.ncbi.nlm.nih.gov/pubmed/25117862
http://dx.doi.org/10.1186/1742-4690-11-60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261571/
https://www.ncbi.nlm.nih.gov/pubmed/25117862
http://dx.doi.org/10.1186/1742-4690-11-60

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