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Automated image-based assay for evaluation of HIV neutralization and cell-to-cell fusion inhibition

BACKGROUND: Standardized techniques to detect HIV-neutralizing antibody responses are of great importance in the search for an HIV vaccine. METHODS: Here, we present a high-throughput, high-content automated plaque reduction (APR) assay based on automated microscopy and image analysis that allows ev...

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Detalles Bibliográficos
Autores principales: Sheik-Khalil, Enas, Bray, Mark-Anthony, Özkaya Şahin, Gülsen, Scarlatti, Gabriella, Jansson, Marianne, Carpenter, Anne E, Fenyö, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261578/
https://www.ncbi.nlm.nih.gov/pubmed/25176034
http://dx.doi.org/10.1186/1471-2334-14-472