Prevention of hyperoxia-induced bronchial hyperreactivity by sildenafil and vasoactive intestinal peptide: impact of preserved lung function and structure

OBJECTIVE: Hyperoxia exposure leads to the development of lung injury and bronchial hyperreactivity (BHR) via involvement of nitric oxide (NO) pathway. We aimed at characterizing whether the stimulation of the NO pathway by sildenafil or vasoactive intestinal peptide (VIP) is able to prevent the hyp...

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Detalles Bibliográficos
Autores principales: Czövek, Dorottya, Peták, Ferenc, Donati, Yves, Belin, Xavier, Pache, Jean-Claude, Barazzone Argiroffo, Constance, Habre, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261898/
https://www.ncbi.nlm.nih.gov/pubmed/25117627
http://dx.doi.org/10.1186/1465-9921-15-81

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261898/
https://www.ncbi.nlm.nih.gov/pubmed/25117627
http://dx.doi.org/10.1186/1465-9921-15-81

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