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Prevention of hyperoxia-induced bronchial hyperreactivity by sildenafil and vasoactive intestinal peptide: impact of preserved lung function and structure
OBJECTIVE: Hyperoxia exposure leads to the development of lung injury and bronchial hyperreactivity (BHR) via involvement of nitric oxide (NO) pathway. We aimed at characterizing whether the stimulation of the NO pathway by sildenafil or vasoactive intestinal peptide (VIP) is able to prevent the hyp...
Autores principales: | Czövek, Dorottya, Peták, Ferenc, Donati, Yves, Belin, Xavier, Pache, Jean-Claude, Barazzone Argiroffo, Constance, Habre, Walid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261898/ https://www.ncbi.nlm.nih.gov/pubmed/25117627 http://dx.doi.org/10.1186/1465-9921-15-81 |
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