B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1

B-RafV600E mutant is found in 40–70% of papillary thyroid carcinoma (PTC) and has an important role in the pathogenesis of PTC. The sodium iodide symporter (NIS) is an integral plasma membrane glycoprotein that mediates active iodide transport into the thyroid follicular cells, and B-RafV600E has be...

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Detalles Bibliográficos
Autores principales: Choi, Yong Won, Kim, Hyun-Ju, Kim, Young Hwa, Park, So Hyun, Chwae, Yong Jun, Lee, Jeonghun, Soh, Euy Young, Kim, Jang-Hee, Park, Tae Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261912/
https://www.ncbi.nlm.nih.gov/pubmed/25378232
http://dx.doi.org/10.1038/emm.2014.68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261912/
https://www.ncbi.nlm.nih.gov/pubmed/25378232
http://dx.doi.org/10.1038/emm.2014.68

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