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Mass Spectrometry Approach and ELISA Reveal the Effect of Codon Optimization on N-Linked Glycosylation of HIV-1 gp120

[Image: see text] The genes encoding many viral proteins such as HIV-1 envelope glycoprotein gp120 have a tendency for codons that are poorly used by the human genome. Why these codons are frequently present in the HIV genome is not known. The presence of these codons limits expression of HIV-1 gp12...

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Detalles Bibliográficos
Autores principales: Honarmand Ebrahimi, Kourosh, West, Graham M., Flefil, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261944/
https://www.ncbi.nlm.nih.gov/pubmed/25285362
http://dx.doi.org/10.1021/pr500740n