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In-Depth Quantitative Proteomic Analysis of de Novo Protein Synthesis Induced by Brain-Derived Neurotrophic Factor

[Image: see text] Measuring the synthesis of new proteins in the context of a much greater number of pre-existing proteins can be difficult. To overcome this obstacle, bioorthogonal noncanonical amino acid tagging (BONCAT) can be combined with stable isotope labeling by amino acid in cell culture (S...

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Detalles Bibliográficos
Autores principales: Zhang, Guoan, Bowling, Heather, Hom, Nancy, Kirshenbaum, Kent, Klann, Eric, Chao, Moses V., Neubert, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261974/
https://www.ncbi.nlm.nih.gov/pubmed/25271054
http://dx.doi.org/10.1021/pr5006982