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Altered Signaling in the G1 Phase Deregulates Chondrocyte Growth in a Mouse Model With Proteoglycan Undersulfation

In several skeletal dysplasias defects in extracellular matrix molecules affect not only the structural and mechanical properties of cartilage, but also the complex network of signaling pathways involved in cell proliferation and differentiation. Sulfated proteoglycans, besides playing an important...

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Detalles Bibliográficos
Autores principales: Leonardis, Fabio De, Monti, Luca, Gualeni, Benedetta, Tenni, Ruggero, Forlino, Antonella, Rossi, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262066/
https://www.ncbi.nlm.nih.gov/pubmed/24820054
http://dx.doi.org/10.1002/jcb.24844