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Altered Signaling in the G1 Phase Deregulates Chondrocyte Growth in a Mouse Model With Proteoglycan Undersulfation
In several skeletal dysplasias defects in extracellular matrix molecules affect not only the structural and mechanical properties of cartilage, but also the complex network of signaling pathways involved in cell proliferation and differentiation. Sulfated proteoglycans, besides playing an important...
Autores principales: | Leonardis, Fabio De, Monti, Luca, Gualeni, Benedetta, Tenni, Ruggero, Forlino, Antonella, Rossi, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262066/ https://www.ncbi.nlm.nih.gov/pubmed/24820054 http://dx.doi.org/10.1002/jcb.24844 |
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