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Prevention of Pazopanib-Induced Prolonged Cardiac Repolarization and Proarrhythmic Effects

BACKGROUND: Pazopanib (PZP) may induce prolonged cardiac repolarization and proarrhythmic effects, similarly to other tyrosine kinase inhibitors. OBJECTIVES: To demonstrate PZP-induced prolonged cardiac repolarization and proarrhythmic electrophysiological effects and to investigate possible prevent...

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Detalles Bibliográficos
Autores principales: Akman, Tulay, Erbas, Oytun, Akman, Levent, Yilmaz, Ahmet U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262101/
https://www.ncbi.nlm.nih.gov/pubmed/25229355
http://dx.doi.org/10.5935/abc.20140138