Distinguishing between driver and passenger mutations in individual cancer genomes by network enrichment analysis

BACKGROUND: In somatic cancer genomes, delineating genuine driver mutations against a background of multiple passenger events is a challenging task. The difficulty of determining function from sequence data and the low frequency of mutations are increasingly hindering the search for novel, less comm...

Descripción completa

Detalles Bibliográficos
Autores principales: Merid, Simon Kebede, Goranskaya, Daria, Alexeyenko, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262241/
https://www.ncbi.nlm.nih.gov/pubmed/25236784
http://dx.doi.org/10.1186/1471-2105-15-308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262241/
https://www.ncbi.nlm.nih.gov/pubmed/25236784
http://dx.doi.org/10.1186/1471-2105-15-308

Ejemplares similares