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Distinguishing between driver and passenger mutations in individual cancer genomes by network enrichment analysis
BACKGROUND: In somatic cancer genomes, delineating genuine driver mutations against a background of multiple passenger events is a challenging task. The difficulty of determining function from sequence data and the low frequency of mutations are increasingly hindering the search for novel, less comm...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262241/ https://www.ncbi.nlm.nih.gov/pubmed/25236784 http://dx.doi.org/10.1186/1471-2105-15-308 |