A promoter mutation in the haemagglutinin segment of influenza A virus generates an effective candidate live attenuated vaccine

BACKGROUND: Annual seasonal and pandemic influenza vaccines need to be produced in a very tight time frame. Haemagglutinin (HA) is the major immunogenic component of influenza vaccines, and there is a lot of interest in improving candidate vaccine viruses. OBJECTIVES: It has been shown elsewhere tha...

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Detalles Bibliográficos
Autores principales: Harvey, Ruth, Johnson, Rachel E, MacLellan-Gibson, Kirsty, Robertson, James S, Engelhardt, Othmar G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262274/
https://www.ncbi.nlm.nih.gov/pubmed/25087607
http://dx.doi.org/10.1111/irv.12274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262274/
https://www.ncbi.nlm.nih.gov/pubmed/25087607
http://dx.doi.org/10.1111/irv.12274

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