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Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice

Hearing relies on the mechanosensory inner and outer hair cells (OHCs) of the organ of Corti, which convert mechanical deflections of their actin-rich stereociliary bundles into electrochemical signals. Several actin-associated proteins are essential for stereocilia formation and maintenance, and th...

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Detalles Bibliográficos
Autores principales: Taylor, Ruth, Bullen, Anwen, Johnson, Stuart L., Grimm-Günter, Eva-Maria, Rivero, Francisco, Marcotti, Walter, Forge, Andrew, Daudet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262491/
https://www.ncbi.nlm.nih.gov/pubmed/25124451
http://dx.doi.org/10.1093/hmg/ddu417