Cargando…

Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen

BACKGROUND: Xenograft rejection of pigs organs with an engineered mutation in the GGTA-1 gene (GTKO) remains a predominantly antibody mediated process which is directed to a variety of non-Gal protein and carbohydrate antigens. We previously used an expression library screening strategy to identify...

Descripción completa

Detalles Bibliográficos
Autores principales: Byrne, Guerard W, Du, Zeji, Stalboerger, Paul, Kogelberg, Heide, McGregor, Christopher G A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262693/
https://www.ncbi.nlm.nih.gov/pubmed/25176027
http://dx.doi.org/10.1111/xen.12124