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Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen
BACKGROUND: Xenograft rejection of pigs organs with an engineered mutation in the GGTA-1 gene (GTKO) remains a predominantly antibody mediated process which is directed to a variety of non-Gal protein and carbohydrate antigens. We previously used an expression library screening strategy to identify...
Autores principales: | Byrne, Guerard W, Du, Zeji, Stalboerger, Paul, Kogelberg, Heide, McGregor, Christopher G A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262693/ https://www.ncbi.nlm.nih.gov/pubmed/25176027 http://dx.doi.org/10.1111/xen.12124 |
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