aPKC Phosphorylates p27Xic1, Providing a Mechanistic Link between Apicobasal Polarity and Cell-Cycle Control

During the development of the nervous system, apicobasally polarized stem cells are characterized by a shorter cell cycle than nonpolar progenitors, leading to a lower differentiation potential of these cells. However, how polarization might be directly linked to the kinetics of the cell cycle is no...

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Detalles Bibliográficos
Autores principales: Sabherwal, Nitin, Thuret, Raphael, Lea, Robert, Stanley, Peter, Papalopulu, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262734/
https://www.ncbi.nlm.nih.gov/pubmed/25490266
http://dx.doi.org/10.1016/j.devcel.2014.10.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262734/
https://www.ncbi.nlm.nih.gov/pubmed/25490266
http://dx.doi.org/10.1016/j.devcel.2014.10.023

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