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Functional Role of Calstabin2 in Age-related Cardiac Alterations

Calstabin2 is a component of the cardiac ryanodine receptor (RyR2) macromolecular complex, which modulates Ca(2+) release from the sarcoplasmic reticulum in cardiomyocytes. Previous reports implied that genetic deletion of Calstabin2 leads to phenotypes related to cardiac aging. However, the mechani...

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Detalles Bibliográficos
Autores principales: Yuan, Qi, Chen, Zheng, Santulli, Gaetano, Gu, Lei, Yang, Zhi-Guang, Yuan, Zeng-Qiang, Zhao, Yan-Ting, Xin, Hong-Bo, Deng, Ke-Yu, Wang, Shi-Qiang, Ji, Guangju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262885/
https://www.ncbi.nlm.nih.gov/pubmed/25502776
http://dx.doi.org/10.1038/srep07425