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Telomere Maintenance Mechanisms in Cancer: Clinical Implications
The presence of immortal cell populations with an up-regulated telomere maintenance mechanism (TMM) is an almost univer-sal characteristic of cancers, whereas normal somatic cells are unable to prevent proliferation-associated telomere shortening and have a limited proliferative potential. TMMs and...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bentham Science Publishers
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262939/ https://www.ncbi.nlm.nih.gov/pubmed/24975603 http://dx.doi.org/10.2174/1381612820666140630101047 |