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Telomere Maintenance Mechanisms in Cancer: Clinical Implications

The presence of immortal cell populations with an up-regulated telomere maintenance mechanism (TMM) is an almost univer-sal characteristic of cancers, whereas normal somatic cells are unable to prevent proliferation-associated telomere shortening and have a limited proliferative potential. TMMs and...

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Detalles Bibliográficos
Autor principal:	Reddel, Roger R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262939/ https://www.ncbi.nlm.nih.gov/pubmed/24975603 http://dx.doi.org/10.2174/1381612820666140630101047

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