Evolutionary link between metazoan RHIM motif and prion-forming domain of fungal heterokaryon incompatibility factor HET-s/HET-s

The Rip homotypic interaction motif (RHIM) is a short, non-globular sequence stretch that mediates a key interaction of mammalian necroptosis signaling. In order to understand its unusual oligomerization properties, we set out to trace the evolutionary origins of the RHIM motif by identifying distan...

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Detalles Bibliográficos
Autores principales: Kajava, Andrey V., Klopffleisch, Karsten, Chen, Shuhua, Hofmann, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262963/
https://www.ncbi.nlm.nih.gov/pubmed/25500536
http://dx.doi.org/10.1038/srep07436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262963/
https://www.ncbi.nlm.nih.gov/pubmed/25500536
http://dx.doi.org/10.1038/srep07436

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