A method for inverse bifurcation of biochemical switches: inferring parameters from dose response curves

BACKGROUND: Within cells, stimuli are transduced into cell responses by complex networks of biochemical reactions. In many cell decision processes the underlying networks behave as bistable switches, converting graded stimuli or inputs into all or none cell responses. Observing how systems respond t...

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Detalles Bibliográficos
Autores principales: Otero-Muras, Irene, Yordanov, Pencho, Stelling, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263113/
https://www.ncbi.nlm.nih.gov/pubmed/25409687
http://dx.doi.org/10.1186/s12918-014-0114-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263113/
https://www.ncbi.nlm.nih.gov/pubmed/25409687
http://dx.doi.org/10.1186/s12918-014-0114-2

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