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A method for inverse bifurcation of biochemical switches: inferring parameters from dose response curves
BACKGROUND: Within cells, stimuli are transduced into cell responses by complex networks of biochemical reactions. In many cell decision processes the underlying networks behave as bistable switches, converting graded stimuli or inputs into all or none cell responses. Observing how systems respond t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263113/ https://www.ncbi.nlm.nih.gov/pubmed/25409687 http://dx.doi.org/10.1186/s12918-014-0114-2 |