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SENIEUR status of the originating cell donor negates certain ‘anti-immunosenescence’ effects of ebselen and N-acetyl cysteine in human T cell clone cultures

BACKGROUND: Damage to T cells of the immune system by reactive oxygen species may result in altered cell function or cell death and thereby potentially impact upon the efficacy of a subsequent immune response. Here, we assess the impact of the antioxidants Ebselen and N-acetyl cysteine on a range of...

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Detalles Bibliográficos
Autores principales: Marthandan, Shiva, Freeburn, Robin, Steinbrecht, Susanne, Pawelec, Graham, Barnett, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263119/
https://www.ncbi.nlm.nih.gov/pubmed/25505928
http://dx.doi.org/10.1186/s12979-014-0017-5