Cargando…

Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit

Cellular senescence is a stable cell cycle arrest that limits the proliferation of pre-cancerous cells. Here we demonstrate that scaffold-attachment-factor A (SAFA) and the long noncoding RNA PANDA differentially interact with polycomb repressive complexes (PRC1 and PRC2) and the transcription facto...

Descripción completa

Detalles Bibliográficos
Autores principales: Puvvula, Pavan Kumar, Desetty, Rohini Devi, Pineau, Pascal, Marchio, Agnés, Moon, Anne, Dejean, Anne, Bischof, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263151/
https://www.ncbi.nlm.nih.gov/pubmed/25406515
http://dx.doi.org/10.1038/ncomms6323