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Genome-wide Profiling of 8-Oxoguanine Reveals Its Association with Spatial Positioning in Nucleus

8-Oxoguanine (8-oxoG) is one of the most common DNA lesions generated by reactive oxygen species. In this study, we analysed the genome-wide distribution profile of 8-oxoG by combining immunoprecipitation by antibodies specific for the DNA fragments containing 8-oxoG with a microarray that covers ra...

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Detalles Bibliográficos
Autores principales: Yoshihara, Minako, Jiang, Li, Akatsuka, Shinya, Suyama, Mikita, Toyokuni, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263294/
https://www.ncbi.nlm.nih.gov/pubmed/25008760
http://dx.doi.org/10.1093/dnares/dsu023