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Genomic Analysis Reveals Distinct Concentration-Dependent Evolutionary Trajectories for Antibiotic Resistance in Escherichia coli

Evolution of bacteria under sublethal concentrations of antibiotics represents a trade-off between growth and resistance to the antibiotic. To understand this trade-off, we performed in vitro evolution of laboratory Escherichia coli under sublethal concentrations of the aminoglycoside kanamycin over...

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Detalles Bibliográficos
Autores principales: Mogre, Aalap, Sengupta, Titas, Veetil, Reshma T., Ravi, Preethi, Seshasayee, Aswin Sai Narain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263303/
https://www.ncbi.nlm.nih.gov/pubmed/25281544
http://dx.doi.org/10.1093/dnares/dsu032