NMDA receptor structures reveal subunit arrangement and pore architecture

N-methyl-d-aspartate (NMDA) receptors are Hebbian-like coincidence detectors, requiring binding of glycine and glutamate in combination with the relief of voltage-dependent magnesium block to open an ion conductive pore across the membrane bilayer. Despite the importance of the NMDA receptor in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Chia-Hsueh, Lü, Wei, Michel, Jennifer Carlisle, Goehring, April, Du, Juan, Song, Xianqiang, Gouaux, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263351/
https://www.ncbi.nlm.nih.gov/pubmed/25008524
http://dx.doi.org/10.1038/nature13548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263351/
https://www.ncbi.nlm.nih.gov/pubmed/25008524
http://dx.doi.org/10.1038/nature13548

Ejemplares similares