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NMDA receptor structures reveal subunit arrangement and pore architecture
N-methyl-d-aspartate (NMDA) receptors are Hebbian-like coincidence detectors, requiring binding of glycine and glutamate in combination with the relief of voltage-dependent magnesium block to open an ion conductive pore across the membrane bilayer. Despite the importance of the NMDA receptor in the...
Autores principales: | Lee, Chia-Hsueh, Lü, Wei, Michel, Jennifer Carlisle, Goehring, April, Du, Juan, Song, Xianqiang, Gouaux, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263351/ https://www.ncbi.nlm.nih.gov/pubmed/25008524 http://dx.doi.org/10.1038/nature13548 |
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