Sliding of Proteins Non-specifically Bound to DNA: Brownian Dynamics Studies with Coarse-Grained Protein and DNA Models

DNA binding proteins efficiently search for their cognitive sites on long genomic DNA by combining 3D diffusion and 1D diffusion (sliding) along the DNA. Recent experimental results and theoretical analyses revealed that the proteins show a rotation-coupled sliding along DNA helical pitch. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Ando, Tadashi, Skolnick, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263358/
https://www.ncbi.nlm.nih.gov/pubmed/25504215
http://dx.doi.org/10.1371/journal.pcbi.1003990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263358/
https://www.ncbi.nlm.nih.gov/pubmed/25504215
http://dx.doi.org/10.1371/journal.pcbi.1003990

Ejemplares similares