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Rgs6 is Required for Adult Maintenance of Dopaminergic Neurons in the Ventral Substantia Nigra

Parkinson disease (PD) is characterized by the preferential, but poorly understood, vulnerability to degeneration of midbrain dopaminergic (mDA) neurons in the ventral substantia nigra compacta (vSNc). These sensitive mDA neurons express Pitx3, a transcription factor that is critical for their survi...

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Detalles Bibliográficos
Autores principales: Bifsha, Panojot, Yang, Jianqi, Fisher, Rory A., Drouin, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263397/
https://www.ncbi.nlm.nih.gov/pubmed/25501001
http://dx.doi.org/10.1371/journal.pgen.1004863