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Genome-Wide Analysis of DNA Methylation Dynamics during Early Human Development

DNA methylation is globally reprogrammed during mammalian preimplantation development, which is critical for normal development. Recent reduced representation bisulfite sequencing (RRBS) studies suggest that the methylome dynamics are essentially conserved between human and mouse early embryos. RRBS...

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Detalles Bibliográficos
Autores principales: Okae, Hiroaki, Chiba, Hatsune, Hiura, Hitoshi, Hamada, Hirotaka, Sato, Akiko, Utsunomiya, Takafumi, Kikuchi, Hiroyuki, Yoshida, Hiroaki, Tanaka, Atsushi, Suyama, Mikita, Arima, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263407/
https://www.ncbi.nlm.nih.gov/pubmed/25501653
http://dx.doi.org/10.1371/journal.pgen.1004868