Cargando…

Single-Molecule Analysis of Thymine Dimer-Containing G-Quadruplexes Formed from the Human Telomere Sequence

[Image: see text] The human telomere plays crucial roles in maintaining genome stability. In the presence of suitable cations, the repetitive 5′-TTAGGG-3′ human telomere sequence can fold into G-quadruplexes that adopt the hybrid, basket, or propeller fold. The telomere sequence is hypersensitive to...

Descripción completa

Detalles Bibliográficos
Autores principales: Wolna, Anna H., Fleming, Aaron M., Burrows, Cynthia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263424/
https://www.ncbi.nlm.nih.gov/pubmed/25407781
http://dx.doi.org/10.1021/bi501072m