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Modifying Caspase-3 Activity by Altering Allosteric Networks
[Image: see text] Caspases have several allosteric sites that bind small molecules or peptides. Allosteric regulators are known to affect caspase enzyme activity, in general, by facilitating large conformational changes that convert the active enzyme to a zymogen-like form in which the substrate-bin...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263430/ https://www.ncbi.nlm.nih.gov/pubmed/25343534 http://dx.doi.org/10.1021/bi500874k |