Cargando…
Electrostatic Properties of Complexes along a DNA Glycosylase Damage Search Pathway
[Image: see text] Human uracil DNA glycosylase (hUNG) follows an extended reaction coordinate for locating rare uracil bases in genomic DNA. This process begins with diffusion-controlled engagement of undamaged DNA, followed by a damage search step in which the enzyme remains loosely associated with...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263432/ https://www.ncbi.nlm.nih.gov/pubmed/25408964 http://dx.doi.org/10.1021/bi501011m |