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Structural Effect of the Asp345a Insertion in Penicillin-Binding Protein 2 from Penicillin-Resistant Strains of Neisseria gonorrhoeae

[Image: see text] A hallmark of penicillin-binding protein 2 (PBP2) from penicillin-resistant strains of Neisseria gonorrhoeae is insertion of an aspartate after position 345. The insertion resides on a loop near the active site and is immediately adjacent to an existing aspartate (Asp346) that form...

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Detalles Bibliográficos
Autores principales: Fedarovich, Alena, Cook, Edward, Tomberg, Joshua, Nicholas, Robert A., Davies, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263433/
https://www.ncbi.nlm.nih.gov/pubmed/25403720
http://dx.doi.org/10.1021/bi5011317