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VWA domain of S5a restricts the ability to bind ubiquitin and Ubl to the 26S proteasome

The 26S proteasome recognizes a vast number of ubiquitin-dependent degradation signals linked to various substrates. This recognition is mediated mainly by the stoichiometric proteasomal resident ubiquitin receptors S5a and Rpn13, which harbor ubiquitin-binding domains. Regulatory steps in substrate...

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Detalles Bibliográficos
Autores principales: Piterman, Ravit, Braunstein, Ilana, Isakov, Elada, Ziv, Tamar, Navon, Ami, Cohen, Shenhav, Stanhill, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263443/
https://www.ncbi.nlm.nih.gov/pubmed/25318673
http://dx.doi.org/10.1091/mbc.E13-11-0697