Alternative splicing of human NT5E in cirrhosis and hepatocellular carcinoma produces a negative regulator of ecto-5′-nucleotidase (CD73)

Ecto-5′-nucleotidase (CD73), encoded by NT5E, is the major enzymatic source of extracellular adenosine. CD73 controls numerous pathophysiological responses and is a potential disease target, but its regulation is poorly understood. We examined NT5E regulation by alternative splicing. Genomic databas...

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Detalles Bibliográficos
Autores principales: Snider, Natasha T., Altshuler, Peter J., Wan, Shanshan, Welling, Theodore H., Cavalcoli, James, Omary, M. Bishr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263446/
https://www.ncbi.nlm.nih.gov/pubmed/25298403
http://dx.doi.org/10.1091/mbc.E14-06-1167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263446/
https://www.ncbi.nlm.nih.gov/pubmed/25298403
http://dx.doi.org/10.1091/mbc.E14-06-1167

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