Cargando…
Alternative splicing of human NT5E in cirrhosis and hepatocellular carcinoma produces a negative regulator of ecto-5′-nucleotidase (CD73)
Ecto-5′-nucleotidase (CD73), encoded by NT5E, is the major enzymatic source of extracellular adenosine. CD73 controls numerous pathophysiological responses and is a potential disease target, but its regulation is poorly understood. We examined NT5E regulation by alternative splicing. Genomic databas...
Autores principales: | Snider, Natasha T., Altshuler, Peter J., Wan, Shanshan, Welling, Theodore H., Cavalcoli, James, Omary, M. Bishr |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263446/ https://www.ncbi.nlm.nih.gov/pubmed/25298403 http://dx.doi.org/10.1091/mbc.E14-06-1167 |
Ejemplares similares
-
Physiological roles for ecto-5’-nucleotidase (CD73)
por: Colgan, Sean P., et al.
Publicado: (2006) -
The Ecto-5′nucleotidase/CD73 Mediates Leishmania amazonensis Survival in Macrophages
por: Bajracharya, Bijay, et al.
Publicado: (2022) -
Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells
por: Rosemblatt, Mariana V., et al.
Publicado: (2021) -
Expression of ecto-5'-nucleotidase (CD73) in normal mammary gland and in breast carcinoma.
por: Krüger, K. H., et al.
Publicado: (1991) -
Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia
por: Thompson, Linda F., et al.
Publicado: (2004)