Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis

The Rho GTPases RhoA and Rac1 function as master regulators of cytokinesis by controlling the actomyosin cytoskeleton. RhoA and Rac1 have to be respectively activated and inactivated at the division plane for cytokinesis to occur properly. The inactivation of Rac1 at the cleavage furrow is controlle...

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Detalles Bibliográficos
Autores principales: Cannet, Aude, Schmidt, Susanne, Delaval, Bénédicte, Debant, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263449/
https://www.ncbi.nlm.nih.gov/pubmed/25355950
http://dx.doi.org/10.1091/mbc.E14-06-1153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263449/
https://www.ncbi.nlm.nih.gov/pubmed/25355950
http://dx.doi.org/10.1091/mbc.E14-06-1153

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