Cargando…

HDAC6–ubiquitin interaction controls the duration of HSF1 activation after heat shock

After heat shock, HSF1 controls a major cellular transcriptional response involving the activation of early (HSP70) and late (HSP25) heat shock gene expression. Here we show that a full response to heat shock (activation of both HSP70 and HSP25) depends on the duration of HSF1 activation, which is i...

Descripción completa

Detalles Bibliográficos
Autores principales: Pernet, Lydia, Faure, Virginie, Gilquin, Benoit, Dufour-Guérin, Solenne, Khochbin, Saadi, Vourc’h, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263459/
https://www.ncbi.nlm.nih.gov/pubmed/25298398
http://dx.doi.org/10.1091/mbc.E14-06-1032